Pneumococcal septic arthritis after splenectomy in Felty's syndrome.
نویسندگان
چکیده
A patient with Felty's syndrome who developed bilateral knee septic arthritis and septicaemia due to Streptococcus pneumoniae is described. She had had a previous splenectomy for symptomatic thrombocytopenia, having received pneumococcal vaccine before the operation. Measurement of antibody to the 23 vaccine serotypes showed protective concentrations before infection to just two. The infecting serotype was not represented in the vaccine, but a vigorous antibody response to this serotype occurred. The patient also developed glomerulonephritis due to immune complex deposition.
منابع مشابه
Felty's syndrome presenting without arthritis.
A patient with splenomegaly, severe granulocytopenia and a strongly positive rheumatoid factor test initially had no clinical evidence of rheumatoid arthritis. Leukopenia responded to splenectomy and did not recur during one year of follow up. Symmetrical metacarpophalangeal joint swelling developed after nine months. This case emphasizes that arthritis may occasionally be a late and minor mani...
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Felty (1924) described five patients with chronic arthritis, splenomegaly, leucopenia, and pigmentation. Since then the association between rheumatoid arthritis, splenomegaly, and leucopenia has been referred to as Felty's syndrome, although it is generally believed that it is not a separate disease entity (Curtis and Pollard, 1940; Short, Bauer, and Reynolds, 1957). The aetiology of the leucop...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 50 10 شماره
صفحات -
تاریخ انتشار 1991